When writing a manuscript be sure to remain patient-centered. It is easy to lose sight of the bigger picture and become bogged down in data and numbers. Avoid emphasis on statistical significance at the expense of clinical significance.
Write for the reader and not to please peer reviewers. Write as if you are talking to an informed colleague or explaining a new technique to an experienced research technician.
Try to write as vividly and descriptively as possible, and be concise.